The reference site for Granisetron

Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.

WHAT IS GRANISETRON?

Granisetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy, radiation therapy, and anesthesia used during surgery.

Its main affect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. However, it does not have much effect on vomiting due to motion sickness.

 

Brand Name(s): Kytril
CAS nº: 109889-09-0
(gra NI se tron)

 

Product Info

The sections below will provide you with more specific information and guidelines related to granisetron and its correct use. Please read them carefully.

FDA Information

Granisetron was first invented by chemists working at the British drug company Beecham around 1988 and it is expected to go generic in 2007/2008.

It is currently produced by Roche Laboratories under the trade name Kytril®. The drug was approved in the United Kingdom in 1991 and in United States in 1994 by the FDA.

Please visit the official site of the FDA for further information.

Why is this medication prescribed?

Granisetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy, radiation therapy, and anesthesia used during surgery.

Its main affect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. On the other hand, it does not have much effect on vomiting caused by motion sickness.

Other uses for this medicine

This medication has not been approved for any alternative uses other than those mentioned in the product information section.

Dosage and using this medicine

Always take granisetron exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

This medication can be taken with or without food, and each oral dose should be taken with a full glass of water.

To ensure you get the correct dose, measure the liquid form of granisetron with a dose-measuring spoon, cup, or dropper and not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

What special precautions should I follow?

BEFORE TAKING GRANISETRON:

Please inform your doctor about any other medical conditions that you have and about any other prescription or over-the-counter medicines, including herbal products, that you might be taking. You may need a dosage adjustment or special monitoring during treatment.

Granisetron is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Nevertheless, do not take granisetron without first talking to your doctor if you are pregnant or if you are planning a pregnancy.

Moreover, it is not known whether granisetron passes into breast milk. Do not take granisetron without first talking to your doctor if you are breast-feeding a baby.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose.

Do not take a double dose of this medication.

What side effects can this medication cause?

Possible side effects from granisetron include:

diarrhea
constipation
change in taste
headache
fever
drowsiness
trouble sleeping
agitation
anxiety

Tell your doctor if any of these symptoms are severe or do not go away:

headache
fatigue, drowsiness, or dizziness
anxiety or agitation
diarrhea or constipation

If you experience any of the following symptoms, call your doctor immediately:

an allergic reaction (swelling of the lips, tongue, or face, difficulty breathing, closing of the throat, or hives)
irregular heartbeats
muscle cramps or uncontrollable movements

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Remember to throw away any medication that is outdated or no longer needed and, should it be required, talk to your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose

In the case of an overdose, please seek emergency medical attention. The only known symptom of a granisetron overdose is a headache.

Product Images

PICTURES OF GRANISETRON MEDICATION

Below you will find images and specific information on the principal types of granisetron that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

 

Name: KYTRIL®
Strength(s): 1 MG/ML
Imprint: KYTRIL
Manufacturer: HOFFMANN-LA ROCHE

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